Can BPC-157 Help With A Herniated Disk?

In this blog, we will investigate whether BPC157 and its healing properties can be beneficial in treating herniated discs and discuss other possible supplements which are scientifically proven to help with such health problems.
Frederika Malichová

Frederika Malichová

Neuroscientist at the University Of Cambridge.

A blue image with text saying "Can BPC157 Help with Herniated Disk?"

Can BPC-157 Help with a Herniated Disk?

The potential use of BPC157 in alleviating symptoms or accelerating the healing of herniated discs has not yet been studied extensively. While BPC157 does appear to have healing properties, more research is needed to determine its effectiveness in treating herniated discs.

What is BPC-157?

Body Protective Compound 157, also known by its abbreviation BPC157, is a compound found in human gastric juice [1, 2].

It is a pentadecapeptide, consisting of 15 amino acids [1].

BPC157 has a short-lasting half-life of less than 30 minutes and is rapidly metabolized into small peptide fragments in the body [1].

This molecule is mainly excreted through urine and bile [1].

BPC157 seems to have protective properties beneficial for various organs and tissues. Additionally, it has been studied for promoting recovery and its potential healing effects in tissues such as the gastrointestinal tract, tendons, and blood vessels [1, 2].

It has also been implicated in angiogenesis (the formation of new blood vessels), supporting its role in healing, particularly in wound healing, by increasing the expression and internalization of VEGFR2, a key receptor in angiogenesis [2].

Furthermore, BPC157 has been shown to accelerate the outgrowth of tendon explants, suggesting a role in promoting tendon healing [3].

Is BPC-157 Beneficial for a Herniated Disc?

BPC157 shows promising results in the healing of nerve and spinal cord injuries in animal studies. While some conclusions can be drawn from these animal studies, direct evidence of its beneficial effects on herniated discs is lacking.

For instance, BPC157 applied immediately after injury significantly improved the healing process in rat sciatic nerves. According to the study, BPC157 accelerated the process of axonal regeneration, increased motor action potentials, and improved functional recovery [4].

Furthermore, a rat study examining the therapeutic effects of BPC157 in spinal cord injury found that rats treated with BPC157 showed consistent clinical improvement, such as better motor function and earlier resolution of spasticity. Microscopically, BPC157 helped injured rats retain axons and prevented the formation of vacuoles in the white matter [3].

These studies suggest potential benefits in nerve and spinal cord healing, which might indicate the potential use of BPC157 for herniated discs. However, it is important to note that these studies were conducted on animals rather than humans.

Can BPC-157 Supplements Help with Herniated Discs?

According to available scientific evidence, BPC157 supplements cannot help with herniated discs. In fact, the effects of BPC157 on herniated discs have not yet been studied in animals or humans. Although some evidence suggests possible beneficial effects of BPC157 on herniated discs, more research is needed to fully understand its therapeutic potential and safety profile [1].

However, other alternative supplements have been scientifically investigated and show the potential to alleviate symptoms of herniated discs and promote healing. Examples include Bone Morphogenetic Proteins (BMP), Matrix Metalloproteinase (MMP), or ozone injections [5, 4].

BMP plays a crucial role in the development and maintenance of intervertebral discs [5]. MMP is important in the natural resorption process of herniated discs [4], and ozone injections were found to reduce pain and disability in patients with low back pain induced by herniated discs [6].

While these treatments show promise, it's crucial to consult with a healthcare provider before starting any new treatment regimen for a herniated disc.

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Frederika Malichová

Frederika Malichová

Frederika is a postgraduate researcher at the University of Cambridge, where she investigates new biomarkers for Frontotemporal Dementia and other tauopathies. Her research has been published at prestigious conferences such as the Alzheimer’s Association International Conference 2023. She obtained her BSc in Biomedical Sciences from UCL, where she worked closely with the UK Dementia Research Institute.