Can iron deficiency cause high blood pressure?
Yes, there are many studies indicating that high blood pressure can occur in people with iron deficiency. However, the connection is not fully understood.
Studies on thousands of participants found that a higher intake of iron is associated with lower blood pressure [1]. On the other hand, low iron consumption was found to increase blood pressure [2].
Another study found similar effects in rat newborns. When the females suffered from iron deficiency during pregnancy, the child had higher blood pressure [3].
All these findings indicate that iron is associated with blood pressure. Even though the exact mechanism is unknown, it is clear that iron deficiency can lead to increased blood pressure.
It is important to note that in most cases of iron deficiency, the blood pressure will not be elevated significantly.
A visible change in blood pressure can be noticed first in severe anemia. In this condition, the heart will beat faster to compensate for the low oxygen in the blood.
What is the normal value of iron in blood?
Several publications mention a slightly different normal range for serum iron levels:
- [1] 60 to 170 mcg/dL
- [3] The mean serum iron concentration is 138.3 ± 32.9 mcg/dL
- [4] 0.47 to 1.75 mg/L (470 to 1750 mcg/L) in men and 0.36 to 1.66 mg/L (360 to 1660 mcg/L) in women
- [5] 65 to 175 mcg/dL in males and 50 to 170 mcg/dL in females
- [6] 108.2 ± 39.5 mcg/dL in males and 88.5 ± 35.7 mcg/dL in females
In summary, the normal range for serum iron levels is generally considered to be:
- Men: 60-180 mcg/dL (10.7-32.2 μmol/L)
- Women: 50-170 mcg/dL (9.0-30.4 μmol/L)
However, it's important to note that serum iron levels can fluctuate throughout the day and can be affected by various factors such as diet, inflammation, and certain medical conditions. Therefore, it's recommended to interpret serum iron levels in conjunction with other iron status indicators like ferritin, transferrin saturation, and total iron-binding capacity (TIBC).
What are the causes of iron deficiency?
Iron deficiency can be caused by many factors. Here are the most common causes of iron deficiency:
- insufficient intake of iron [4]
- blood loss, for example, from menstrual bleeding or gastrointestinal bleeding conditions [4]
- poor iron absorption, like in celiac disease [4]
- parasitic infections [5].
Should you visit a doctor if you have iron deficiency?
Iron deficiency is the most common cause of anemia in the world. Iron is a crucial element in your life. It can be found in hemoglobin, a key component of red blood cells.
The main function of iron in red blood cells is the binding and transport of oxygen from the lungs to the tissues. In iron deficiency, this function decreases. With time, less and less oxygen is available for the organs.
In severe iron deficiency anemia, your internal breathing is impaired. Even when you are breathing, your cells may not get enough oxygen.
Therefore, when you experience characteristic symptoms, you must visit a doctor. Once the physician confirms the iron deficiency, in most cases, it can be easily corrected.
What are the symptoms of iron deficiency?
Iron deficiency can manifest in a variety of ways, many of which may initially go unnoticed.
Common symptoms include:
- fatigue [6]
- weakness [6]
- pale skin [7, 8]
- shortness of breath [7, 8]
- dizziness or headaches [6]
- brittle nails concavity or spoon-shaped depressions [6]
- fast heartbeat [7, 8]
- cravings for ice or dirt [7, 8]
- cold hands and feet [6]
- tingling or a crawling feeling in the legs [7, 8]
- difficulty concentrating and mood changes [9].
Should you pay attention to your iron levels?
If you are a pregnant woman, you need to screen for iron deficiency [10]. Appropriate levels of iron ensure the proper development of the fetus.
Also, one-year-old children should be controlled for their iron levels [10]. Especially at a young age, the demand for iron is high.
Additionally, women who experience heavy periods should remember to investigate their iron levels [11]. If you have heavy bleeding, you should pay attention to your diet and possible symptoms of iron deficiency.
People with gastrointestinal problems like Crohn’s disease or colorectal cancer should also review their iron blood concentration [11]. Especially, chronic bleeding often causes unnoticed iron deficiency. When you see blood in your stool or your stool is black without a known reason, you should visit a doctor as soon as possible.