Can Alcohol Cause Parkinson’s Disease?
Yes, there is some evidence indicating increased alcohol consumption can lead to increased risk of Parkinson's disease (PD) [1].
There is cellular-level evidence indicating alcohol can contribute to neural cell damage and promote inflammation, both of which are processes leading up to the development of neurodegenerative conditions [2]. Furthermore, chronic alcohol consumption changes the neurotransmitter balance in the brain, including reduction in dopamine levels. This can, over time, worsen symptoms of PD [3].
Nonetheless, the link between alcohol consumption and Parkinson's Disease is not fully clear. A recent meta-analysis found that beers reduced PD risk, whereas wine and hard spirits would increase PD risk. The protective factors in moderate alcohol consumption may be because it can alleviate motor symptoms of PD, such as slowness of movement [4].