Does Xanax Cause Weight Gain?
No, there isn't solid evidence to suggest that Xanax (the brand name for alprazolam) directly causes weight gain. Xanax is a form of benzodiazepine that acts on the GABA neurotransmitter system, calms the brain, and so is FDA-approved to manage anxiety and panic attacks [1]. Although weight gain or appetite changes are listed as a common, mild side effect, this is highly heterogeneous across individuals [1]. The evidence for weight gain while taking Xanax is not as well documented as weight gain while taking other psychoactive medications, such as antipsychotics and antidepressants [2, 3].
If you observe substantial weight gain after being prescribed Xanax, make sure to consult your medical professional.