In What Stage of Dementia Does Weight Loss Occur?

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Frederika Malichová

Frederika Malichová

Neuroscientist at the University Of Cambridge.

Weight Loss and Dementia

Weight loss usually occurs in more advanced stages of dementia. Weight loss is not a direct symptom of dementia, but it is known as an accompanying symptom in dementia. As the disease is progressing and the patient is getting into a more advanced stage of the disease, weight loss can be observed.

Around 57% of people in advanced stages of dementia experience chewing and swallowing problems. Difficulties with chewing and swallowing can lead to weight loss or malnutrition [1].

In addition, a study by Soysal et al found out that weight loss was associated with an increased mortality in patients suffering from Alzheimer’s disease [2, 3]. This suggests that weight loss occurs in more advanced stages of dementia.

The term dementia groups all the neurodegenerative diseases resulting in cognitive decline.

Alzheimer’s disease is the most common type of dementia. Apart from Alzheimer’s, sporadic frontotemporal dementia and familial frontotemporal dementia, dementia with Lewy bodies and vascular dementia also belong to the group of dementias.

Frederika Malichová

Frederika Malichová

Frederika is a postgraduate researcher at the University of Cambridge, where she investigates new biomarkers for Frontotemporal Dementia and other tauopathies. Her research has been published at prestigious conferences such as the Alzheimer’s Association International Conference 2023. She obtained her BSc in Biomedical Sciences from UCL, where she worked closely with the UK Dementia Research Institute.