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Lion's Mane and Vyvanse

In this blog, we will closely examine Lion's Mane, a medicinal mushroom known for its potential brain-boosting benefits, and Vyvanse, a prescription medication used to treat ADHD and binge eating disorders.

Nithishwer Mouroug Anand

Author - Nithishwer Mouroug Anand

Nithish is a computational biochemist at the University of Oxford working on alchemical methods for protein-drug interactions.

Nithishwer used MediSearch to find sources for this blog.
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What Is Lion's Mane?

Lion's Mane is a medicinal mushroom known for its potential brain-boosting benefits. It's named for its unique, shaggy appearance that resembles a lion's Mane. This mushroom is packed with antioxidants and is known to strengthen the immune system. It's unique because it fosters the production of the bioprotein nerve growth factor (NFG) and myelin, which are crucial to brain health. Lion's Mane has been shown to improve cognition, memory, and concentration and alleviate anxiety and irritability [1].

Uses Of Lion's Mane

Lion's Mane, as discussed before, is a medicinal mushroom used traditionally in Asia and Europe for its potential benefits in fighting infection and cancer [2]. It has gained interest in neurodegenerative disease treatment due to its anti-inflammatory and neuroprotective properties and ability to promote neurite growth [2].

In a small, double-blind, placebo-controlled trial, Lion's Mane temporarily improved cognitive function in patients with mild cognitive impairment [2]. Another study found that Lion's Mane significantly improved the number of attempts during Serial 7s, reaction time during N-Back, and Go stimulus reaction time in Go/No-go [3].

Lion's Mane has also improved short-term memory in healthy mice [4]. Furthermore, it has been suggested that Lion's Mane may be used to treat anxiety, depression, or nerve problems [5].

Side Effects Of Lion's Mane

While Lion's Mane is usually safe and inexpensive when consumed in powder or capsule form, a case of anaphylaxis (a severe allergic reaction) has been reported after a patient consumed fresh Lion's Mane mushroom [2].

What Is Vyvanse?

Vyvanse is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and binge eating disorder. It's a stimulant that works by restoring the balance of certain natural chemicals (neurotransmitters) in the brain.

Uses Of Vyvanse

In addition to treating ADHD, Vyvanse is also used to treat moderate to severe binge eating disorder in adults. Vyvanse can help increase attention and decrease impulsiveness and hyperactivity in people with ADHD. It's not a supplement and should only be used under the supervision of a healthcare provider.

This medication is not intended for weight loss. It's important to note that the use of Vyvanse should be part of a total treatment program for ADHD that may include counselling or other therapies.

Side Effects of Vyvanse

Common side effects include:

  • Decreased appetite
  • Dry mouth,
  • Irritability, dizziness,
  • Nausea or vomiting,
  • Stomach pain,
  • Diarrhoea or constipation,
  • Sleep problems
  • Blood circulation problems in fingers and toes [6].

More severe side effects can include:

  • Hallucinations
  • Delusions
  • Paranoia
  • Increased blood pressure and heart rate
  • Heart attack
  • Stroke
  • Sudden death

These risks are higher if you have heart problems or heart disease. Vyvanse can also cause new or worsening symptoms in people who have bipolar disorder, thought problems, or psychosis. These symptoms may include delusions, hallucinations, and mania [6].

Vyvanse can also cause emotional side effects, including anger, depression, irritability, and mood changes [7].

In rare cases, Vyvanse can cause serious side effects such as:

  • Blood flow problems in fingers and toes
  • Heart problems
  • Mental health conditions
  • Serotonin syndrome
  • Slowed growth in children
  • Depression
  • Allergic reactions
  • Dependence and misuse may lead to thoughts of harming yourself or others [7].

If you experience severe side effects while taking Vyvanse, it is essential to seek immediate medical attention [7, 8].

Choosing What's Best For You

When choosing a supplement or medication, it's essential to consider your health needs, potential side effects, and the cost. Lion's Mane is a natural supplement that may support cognitive function and mental clarity. However, it's important to note that the effects of supplements can vary significantly between individuals, and the FDA does not regulate them like medications.

Vyvanse, on the other hand, is regulated by the FDA and is used to treat specific conditions like ADHD. It's important to discuss with your healthcare provider if this medication is suitable for you.

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