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Ozempic Injection Bubble Under Skin: Is It Dangerous?

In this article, we will take a close look at Ozempic, a prescription medication used to manage type 2 diabetes. We will explore its uses, potential side effects, and proper injection techniques. Additionally, we will address the occurrence of a bubble under the skin following an Ozempic injection.

Nithishwer Mouroug Anand

Author - Nithishwer Mouroug Anand

Nithish is a computational biochemist at the University of Oxford working on alchemical methods for protein-drug interactions.

Nithishwer used MediSearch to find sources for this blog.
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What is Ozempic?

Ozempic, known by its generic name semaglutide, is a prescription medication used in adults with type 2 diabetes. It is administered as an injection under the skin and belongs to a group of drugs called glucagon-like peptide-1 receptor agonists. This class of drugs works by mimicking the action of a hormone in your body, GLP-1, which helps regulate blood sugar levels and appetite [1, 2].

Uses of Ozempic

Ozempic primarily regulates blood sugar levels in people with type 2 diabetes. It is part of a comprehensive treatment plan that includes a healthy diet and regular exercise. In addition to its role in managing diabetes, Ozempic is also used to reduce the risk of heart-related problems, such as heart attack and stroke, in people with type 2 diabetes and heart disease [1, 3].

Although not officially approved for this use, Ozempic may be prescribed off-label for weight loss. The medication can help reduce appetite, which may lead to a decrease in calorie intake and subsequent weight loss. However, it's important to note that Ozempic is not an FDA-approved weight loss medicine [4].

Ozempic side effects?

Ozempic, a medication used to manage type 2 diabetes, can cause a variety of side effects.

Common side effects: Most common include stomach problems such as nausea, vomiting, diarrhoea, pain, and constipation [3]. These symptoms are usually mild to moderate and tend to clear up within a few weeks for most people [3].

Another common side effect is low blood sugar (hypoglycemia), mainly when Ozempic is used with certain other diabetes treatments. This can be a severe condition, so it's essential to monitor your blood sugar levels regularly [3].

In some cases, Ozempic can cause changes in taste, also known as dysgeusia. This side effect is often discussed on blog sites and affects more than 0.4% of people who take Ozempic [5, 6].

Uncommon side effects: Although less common, Ozempic can also cause more severe side effects. These include diabetic retinopathy (damaged blood vessels in the eye), gallbladder disease (including gallstones or cholecystitis), kidney problems, pancreatitis (swelling of the pancreas), and an increased risk of thyroid cancer [7].

Rare Side effects: In rare cases, Ozempic can cause allergic reactions. Symptoms of a mild allergic reaction can include rash, itchiness, and flushing (temporary warmth, redness, or deepening of skin colour). A more severe allergic reaction can be swelling under your skin, typically in your eyelids, lips, hands, or feet. They can also include tongue, mouth, or throat swelling, which can cause trouble breathing [2].

If you experience any of these side effects, it's essential to consult with your healthcare provider. If the side effects seem life-threatening or you think you have a medical emergency, call 911 or your local emergency number immediately [4].

Ozempic injection bubble under skin

Ozempic medication is administered through subcutaneous injections, typically in the abdomen, upper arm, or thigh [1].

It's important to note that any injection, including Ozempic, can cause a bubble or lump under the skin if administered incorrectly. This could be due to factors such as injecting too quickly, not rotating injection sites, or not allowing the medication to reach room temperature before injecting [4].

If you notice a bubble or lump under your skin after an Ozempic injection, it's recommended to consult with a healthcare professional. They can guide and ensure you administer the injection correctly to prevent future occurrences.

Remember, it's crucial to follow the instructions provided by your healthcare provider or pharmacist when administering Ozempic injections. This includes using a new needle each time, rotating your injection site, and checking that you've clicked on the correct dose on the pen [1].

How to inject Ozempic?

Injecting Ozempic involves steps that ensure the medication is administered safely and effectively.

1. Firstly, gather your supplies. This includes the Ozempic pen, a new needle, an alcohol swab, gauze, and a needle disposal container [1].

2. Before you begin, wash your hands thoroughly to minimise the risk of infection [1, 2].

3. Attach a new needle to the pen and check that the medication inside is clear and colourless [4].

4. Ensure that you've clicked on the correct dose on the pen, which may be 0.25 milligrams (mg), 0.5 mg, 1 mg, or 2 mg [1].

5. The injection is administered under the skin of your abdomen, upper arm, or thigh [1, 2].

6. Rotate your injection site each time you inject the drug to avoid pain and risk of infection [1, 2].

7. After the injection, dispose of the used needle in a puncture-proof "sharps" container [3].

Remember to record the date that your Ozempic prefilled pens should be discarded. They expire 56 days after opening [2].

If you're new to self-injections, don't hesitate to ask your doctor or pharmacist to show you the process again. They are there to help you [2].

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