What is Zyrtec?
Zyrtec, also known by its generic name cetirizine, is an antihistamine commonly used to relieve allergy symptoms. Histamine is known for causing allergy symptoms, so blocking it helps prevent symptoms of seasonal allergies or hay fever. Some studies have found that Zyrtec's beneficial effects last longer than other antihistamines [1].
A division of Johnson & Johnson produces Zyrtec, which is available over the counter without a prescription [2]. Zyrtec works by reducing or blocking the action of histamines, chemicals produced by the body in response to allergens. This action helps alleviate allergic rhinitis (hay fever) symptoms and other allergies, such as runny nose, sneezing, itching, and watery eyes [2].
What is Prednisone?
Prednisone is a type of corticosteroid that is often used to reduce inflammation and suppress the immune system. It can treat conditions like arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone can help reduce swelling, redness, itching, and allergic reactions.
Prednisone is often used in combination with other drugs to treat various conditions. For instance, it is used alongside abiraterone acetate (Zytiga) for the treatment of metastatic castration-resistant prostate cancer (mCRPC) [3, 4]. Prednisone works by decreasing the amount of certain hormones in the body, thereby helping to manage the symptoms of certain conditions [5].
While both Zyrtec and Prednisone are used to manage symptoms of certain conditions, they work in different ways and are used to treat various conditions. Zyrtec is primarily used for relieving allergy symptoms, while Prednisone is combined with other drugs for treating conditions like mCRPC.
Zyrtec Side Effects
Some common side effects of Zyrtec include drowsiness, excessive tiredness, stomach pain, dry mouth, cough, diarrhoea, and vomiting.
Severe side effects can include difficulty breathing or swallowing. It would be best to inform your doctor about any side effects you experience while taking Zyrtec [2, 6].
Prednisone Side Effects
Common side effects of Prednisone can include fluid retention, high blood pressure, changes in blood sugar levels, weight gain, nausea, vomiting, and diarrhoea.
More severe side effects can include mood or behavioural changes, insomnia, increased risk of infection due to immunosuppression, osteoporosis, and eye changes such as glaucoma or cataracts. In children, Prednisone may negatively affect growth or development. In some cases, Prednisone can cause serious side effects like vision problems, seizures, depression, and muscle twitching or tightening [7, 8, 9].
It's important to note that not everyone taking these medications will experience these side effects, which may also vary in severity. Always consult your healthcare provider if you have concerns about potential side effects.
Can hey be taken together?
Zyrtec and Prednisone can be taken together. There is no known interaction between these two medications. However, it's always essential to consult with your healthcare provider before starting any new medication regimen. They can provide personalised advice based on your health history and current medications.
Remember, while Zyrtec and Prednisone may not interact with each other, they can interact with other medications. Always keep your healthcare provider informed about all the medicines and supplements you are taking to avoid potential drug interactions.