Does Coffee Affect Myasthenia Gravis?

In this blog, we will explore the effects of coffee consumption on myasthenia gravis. Together we will go through myasthenia gravis, a chronic autoimmune disease, its causes, and various forms. Additionally, we will explore the potential implication of coffee consumption on myasthenia gravis.
Frederika Malichová

Frederika Malichová

Neuroscientist at the University Of Cambridge.

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Does Coffee Affect Myasthenia Gravis?

There are no scientific studies providing information on whether coffee drinking or coffee consumption affects myasthenia gravis.

It is important to consult with a healthcare professional for personalized advice. Coffee, in general, is linked with many benefits.

What Is Myasthenia Gravis?

Myasthenia gravis (MG) is a long-term autoimmune condition affecting the peripheral nervous system [1].

It is characterized by fluctuating skeletal muscle weakness, fatigue, and potentially even respiratory difficulties [2].

MG is caused by antibodies directed towards proteins (like AchR, MuSK, or rapsyn), which are concentrated at the neuromuscular junction and disrupt the normal communication between nerve cells and muscles [3, 4].

It is an autoimmune disease of the neuromuscular junction, which means the body's immune system mistakenly attacks its own tissues [5].

MG can affect people at any age, however, it is more prevalent in young women or older individuals [5].

The prevalence of MG ranges between 150 to 200 cases per million [3].

There are different clinical manifestations of MG such as difficulty walking, droopy eyelids, or double vision, but the core one is muscle weakness. That may affect ocular, bulbar, respiratory, or limb muscles [3] and worsen with the use of the muscles [1].

Although MG is a serious condition, patients suffering from it can be treated effectively and the condition can be managed well [6].

Is Coffee Drinking Beneficial For Patients Suffering From Myasthenia Gravis?

Although there are no direct studies on how and whether coffee drinking is beneficial for patients with myasthenia gravis, we can explore studies indirectly linking MG and coffee.

Caffeine, contained in coffee, is known to affect neuromuscular function. In MG patients, muscle weakness is primarily due to failure of neuromuscular transmission.

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Frederika Malichová

Frederika Malichová

Frederika is a postgraduate researcher at the University of Cambridge, where she investigates new biomarkers for Frontotemporal Dementia and other tauopathies. Her research has been published at prestigious conferences such as the Alzheimer’s Association International Conference 2023. She obtained her BSc in Biomedical Sciences from UCL, where she worked closely with the UK Dementia Research Institute.