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Enterobacter Vs Enterococcus: A Comparison

In this article, we will take a close look at Enterobacter and Enterococcus, two distinct genera of bacteria. We will explore their typical habitats, the types of infections they cause, and their varying levels of antibiotic resistance.

Nithishwer Mouroug Anand

Author - Nithishwer Mouroug Anand

Nithish is a computational biochemist at the University of Oxford working on alchemical methods for protein-drug interactions.

Nithishwer used MediSearch to find sources for this blog.
MediSearch gives instant answers to medical questions based on 30 million scientific articles.

Enterobacter

Enterobacter is a group of bacteria often linked to hospital infections. But here’s the twist—not all its 22 species are infection-causing. Some are present harmlessly in the gut, while others appear on skin, water, soil, or certain foods [1].

When it does cause infections, it’s no small matter. Enterobacter is behind hospital-acquired issues like UTIs, lung infections, skin problems, and even bone or endocarditis. It’s less common to see these infections pop up outside hospital settings, but it can happen [1].

But it’s not all bad. Some species of Enterobacter help plants grow and even produce bacterial cellulose, which has useful industrial applications [2].

Enterococcus

Enterococcus is a group of bacteria that usually live harmlessly in the human gut and female genital tract. They’re part of your body’s normal microbiome. But they can turn from friendly neighbours into serious troublemakers under certain conditions.

Enterococcus can cause infections like UTIs, bloodstream infections (bacteremia), endocarditis (a heart infection), and even meningitis for people with weakened immune systems. What makes these infections tricky is the bacteria’s knack for survival. Enterococci can thrive in harsh environments and are notoriously resistant to many antibiotics.

Differences between Enterobacter and entereococcus

Enterobacter is a genus of the family Enterobacteriaceae. These bacteria are Gram-negative, facultatively anaerobic, and motile. They are commonly found in the environment, including water and soil, and can also be found in the human gut. Some species of Enterobacter are known to cause hospital-acquired infections.

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In conclusion, Enterobacter and Enterococcus are different genera of bacteria with distinct characteristics. They differ in their Gram staining, motility, typical habitats, types of infections they cause, and their levels of antibiotic resistance.

Enterobacter infection

Enterobacter bacteria are opportunistic troublemakers, often lurking in healthcare settings. While most cases are linked to hospitals, they can occasionally strike outside, causing community-acquired infections, too [1].

One name dominates when we talk about Enterobacter infections: Enterobacter cloacae. It’s responsible for 65-75% of infections, with bacteremia (a bloodstream infection) being the most common scenario [3].

But E. cloacae doesn’t stop there. These infections can manifest in different ways—urinary tract infections, respiratory infections, soft tissue complications, osteomyelitis, endocarditis, sepsis, and pneumonia [1, 4].

It’s no surprise that these infections thrive in hospitals. Patients with prolonged illnesses, those on antibiotics or corticosteroids, and anyone who’s undergone invasive procedures are particularly vulnerable [5, 6]. However, even people without serious underlying conditions or hospital exposure aren’t entirely off the hook—community-acquired cases can happen, though they’re less common [3].

The most common red flag is a fever, reported in about 92% of cases. Severe symptoms like shock occur in nearly a third of patients, though complications such as disseminated intravascular coagulation are rare [7].

What makes Enterobacter especially tricky is its ability to resist treatment. These bacteria are notorious for adapting and becoming antibiotic-resistant, even while being treated [5]. This resistance isn’t just a nuisance—it’s a major reason Enterobacter infections are becoming more prominent in healthcare discussions.

Despite their resistance, Enterobacter infections can be managed effectively with the right approach. Rapid identification and prompt, targeted antimicrobial treatment make all the difference [4].

Enterobacter infections highlight the complex interplay between modern medicine and microbial adaptation. By understanding how these bacteria operate and who they target, healthcare professionals can stay one step ahead in managing and preventing their spread.

Entereococcus infection

Enterococcus bacteria are natural residents of the human gut, but they can become troublemakers when given the chance. Infections caused by these bacteria are often seen in people who are already sick, hospitalised, or have weakened immune systems [8].

Let’s start with Enterococcus durans. It’s not a name you hear every day because infections caused by this species are rare. When they do happen, it’s often in people with compromised health. This bacterium can cause conditions like urinary tract infections, wound infections, and even infective endocarditis. In severe cases, it’s been linked to blood access infections and aneurysms, both of which require immediate medical attention and antibiotic treatment [9].

Then there’s Enterococcus innesii. This is a newer addition to the list of troublemakers and is often mistaken for the more common E. casseliflavus. But don’t be fooled—E. innesii has been tied to biliary sepsis, a dangerous infection of the bile ducts that can escalate quickly if left untreated [10].

Another one to watch is Enterococcus hirae. This species is more often found in animals, but when it infects humans, it doesn’t mess around. It’s been associated with serious conditions like acute pyelonephritis and acute cholangitis—both of which need targeted antibiotics to keep under control [11].

Of course, the big players in Enterococcus infections are E. faecium and E. faecalis. E. faecium, especially its vancomycin-resistant strains, is notorious in hospital settings. These bacteria are behind post-surgical wound infections, catheter-related colonisation, and UTIs, making recovery harder for vulnerable patients [8].

These infections are a stark reminder that even the most ordinary gut bacteria can turn dangerous in the right conditions. Early diagnosis and effective treatment are key to managing their impact.

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