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Superdrol vs Dianabol: How Safe Are They?

In this article, we will take a close look at Superdol and Dianabol, two synthetic steroidal drugs often used for muscle growth. We will discuss their uses, potential side effects, and how safe their use is.

Nithishwer Mouroug Anand

Author - Nithishwer Mouroug Anand

Nithish is a computational biochemist at the University of Oxford working on alchemical methods for protein-drug interactions.

Nithishwer used MediSearch to find sources for this blog.
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What is Superdrol?

Superdrol, also known as Methasterone, is a synthetic steroidal drug used as a supplement to increase weight or accelerate the build-up of muscle mass [1]. It is an anabolic-androgenic steroid that promotes muscle growth and development [2].

What is Dianabol?

Dianabol, also known as methandrostenolone, is an anabolic steroid that has been used for various purposes. It's a synthetic substance related to the male sex hormone testosterone. Bodybuilders and athletes often use Dianabol to enhance physical performance and muscle growth [3, 4].

Superdrol vs Dianabol: Uses

Uses of Superdrol

Apart from its use as a muscle-building supplement, methasterone has also been studied for its anti-inflammatory activity. One study found that methasterone showed remarkable anti-inflammatory activity against nitric oxide (NO) production, with its metabolites showing moderate inhibition [3].

Uses of Dianabol

Dianabol is primarily used to improve nitrogen balance and skeletal muscle composition. In a study involving rats, adding Dianabol to a diet significantly enhanced the biological value and net protein utilization [3].

Moreover, Dianabol has been used in research to study its effects on the degradation rate of myofibrillar proteins in various muscle types. The study found that Dianabol treatment decreased the degradation rate of myofibrillar proteins in all muscle types in the trained group receiving Dianabol [5].

Superdrol vs Dianabol: Side effects

Side effects of Superdrol

Superdrol has been linked to severe liver toxicity that can cause liver damage. Liver failure can worsen within two weeks of initial symptoms, especially after stopping the drug. However, with close observation and supportive care, acute hepatic injury should be cured[1].

Side effects of Dianabol

Dianabol can cause lowered plasma LH levels, which can affect hormonal balance. However, it was not found to significantly alter body weight, specific gravity, lean body weight, fat, or %fat in trained groups [6].

Long-term use of Dianabol can lead to structural alterations of liver parenchyma, including cholestasis, peliosis hepatis, and diffuse hepatitis. It has been suggested that anabolic steroids may not primarily induce the formation of liver tumors, but they can contribute to the development of liver diseases [7].

General side effects of steroids

In addition to these specific effects, anabolic steroids, in general, can cause a range of side effects. These may include acne, facial flushing, depression, swelling of the hands and feet from fluid and sodium retention, headache, increased appetite, increased blood glucose, increased blood pressure, insomnia, lowered resistance to infection, muscle weakness, and stomach irritation or ulcers, and gynecomastia [8].

Long-term steroid treatment can potentially lead to additional side effects such as cataracts, worsening glaucoma, diabetes, osteoporosis, and weight gain [8].

Superdrol vs Dianabol: Are they safe?

Superdrol has been associated with severe hepatotoxicity, leading to liver damage. In one case, a patient was hospitalized for liver damage after consuming supplements containing methasterone [1, 9]

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